Ulcerative colitis and perinuclear antineutrophil cytoplasmic antibodies

Target Antigens for Perinuclear Antineutrophil Cytoplasmic Antibodies in Iranian Patients with Ulcerative Colitis

UNLABELLED BACKGROUND Patients with ulcerative colitis (UC) carry autoantibodies such as perinuclear antineutrophil cytoplasmic antibodies (p-ANCA). OBJECTIVE The aim of the present study was to evaluate the target antigens for p-ANCA in Iranian patients with UC. METHODS p-ANCA target antigens including elastase, lactoferrin, cathepsin G, myeloproxidase, lysozyme, and bactericidal permeabilit...

target antigens for perinuclear antineutrophil cytoplasmic antibodies in iranian patients with ulcerative colitis

background: patients with ulcerative colitis (uc) carry autoantibodies such as perinuclear antineutrophil cytoplasmic antibodies (p-anca). objective: the aim of the present study was to evaluate the target antigens for p-anca in iranian patients with uc. methods: p-anca target antigens including elastase, lactoferrin, cathepsin g, myeloproxidase, lysozyme, and bactericidal permeability increasi...

antineutrophil cytoplasmic autoantibodies in ulcerative colitis

antineutrophil cytoplasmic autoanibodies (anca) were detecte in patients with certain autoimmune vascular disease such as wegner’s granulomatosis, polyarthrits nodosa and systemic luuc erythematous. indirect immunofluorescence (iif) technique was employed to detec these autoantibodies.anca have been recently detected in some forms of inflammatory bowel disease (ibd), ulcerative colitis (u.c). c...

Clinical Implications and Utility of Antineutrophil Cytoplasmic Antibodies in Rheumatoid Arthritis, Spondylarthropathy and Ulcerative Colitis

Soluble interleukin-2 receptors, antineutrophil cytoplasmic antibodies, and other autoantibodies in patients with ulcerative colitis.

Ulcerative colitis (UC) is an inflammatory bowel disease of unknown aetiology. In this study, serum samples from 80 patients with UC were studied for the presence of various autoantibodies and soluble interleukin-2 receptor molecules (sIL-2Rs) in an attempt to determine the degree of activation of the immune system in this disease process. Autoantibodies detected included rheumatoid factors (in...